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US

Exo- and Diastereo- Selective Synthesis of Himbacine Analogs

US 8,618,314 Lapsed on the fee record
OverviewFamilyAssignmentsSources & methods

Lapsed Dec 31, 2025 on the fee record · High confidence

Third maintenance fee unpaid; grace period ended.

Filed Jul 31, 2012 as application 13/563,136 · Granted Dec 31, 2013
Base term, 20 years from filing
Today
Lapsed Dec 31, 2025
2006 2026
Clock starts
Jan 12, 2006
No longer in force
Dec 31, 2025
Granted
Dec 31, 2013
Term would have run to
Jan 12, 2026
base term after the term ends fee events Updated Nov 15, 2026 · includes USPTO assignment & status data published Nov 15, 2026 and grant & fee data published Nov 10, 2026 (weekly) · how we know
None
Term adjustment
No prosecution delay on this record.
None
Terminal disclaimer
No disclaimer on this record.
2 of 3
Maintenance fees paid
Three maintenance fees fall due, at 3.5, 7.5 and 11.5 years from grant. This counts the ones the record shows paid.
4
Family applications on record here
Applications sharing this one's continuity chain whose file history this site holds. The family may have others.

Its term would have run to Jan 12, 2026: its 20-year base term, with no adjustment for prosecution delay. Confidence: High. from the record

How we calculated this date

One row per rule, each showing its own input and what it did to the date. A step we could not verify says so instead of resolving itself.
StepInputDate after this stepConfidence
Base term, 20 years from filingClock starts Jan 12, 2006, when application 11/331,324, the earliest non-provisional in its chain, was filed (this one was filed Jul 31, 2012)Jan 12, 2026High confidence
Continuity chainEvery parent in the chain resolvedno changeHigh confidence
Patent term adjustmentNone on fileno changeHigh confidence
Terminal disclaimer capNone on recordno cap appliedHigh confidence
Patent term extensionNone on fileno changeHigh confidence
Fee events2 of 3 maintenance fees paidlapsed Dec 31, 2025High confidence
Computed term endThe steps above, in orderDec 31, 2025High confidence

This family

US 7,605,275In force
May 2028
May 2028
US 7,989,653Term ended
Jan 2026
Jan 2026
US 8,258,319Lapsed on the fee record
Sep 2024
Sep 2024
US 8,618,314this patent
Dec 2025
Dec 2025
The applications whose file history this site holds. The family may have others.

Assignments

Assignment documents as recorded at the USPTO, oldest first, with the reel and frame each was recorded at. A recorded assignment is a filed document, not a statement of current ownership, and the absence of a later one is not evidence that the last one still stands.
RecordedAssignorAssigneeConveyance
Sep 16, 2016
Reel 39767, frame 695
Merck Sharp & Dohme Corp.Aralez Pharmaceuticals Trading DacAssignment of Assignor's Interest
Sep 29, 2016
Reel 39892, frame 309
Aralez Pharmaceuticals Trading DacDeerfield Private Design Fund III, L.P.; Deerfield International Master Fund, L.P.; Deerfield Partners, L.p.Security Interest
Sep 29, 2016
reel/frame not recorded
Aralez Pharmaceuticals Trading DacDeerfield Private Design Fund III, L.P.Security Interest
Sep 29, 2016
reel/frame not recorded
Aralez Pharmaceuticals Trading DacDeerfield International Master Fund, L.P.Security Interest
Sep 29, 2016
reel/frame not recorded
Aralez Pharmaceuticals Trading DacDeerfield Partners, L.p.Security Interest
Aug 24, 2018
Reel 46696, frame 772
Aralez Pharmaceutical Trading DacDeerfield Management Company, L.P., as Administrative AgentSecurity Interest
Aug 30, 2018
Reel 46988, frame 741
Aralez Pharmaceuticals Trading Designated Activity CompanyDeerfield Management Company, L.P., as Administrative AgentCorrective Assignment to Correct the Conveying Party Previously Recorded at Reel: 046696 Frame: 0772. Assignor(S) Hereby Confirms the Assignment.
Aug 31, 2018
Reel 46989, frame 669
Merck Sharp & Dohme Corp.Aralez Pharmaceuticals Trading DacReceiving Party/Assignee Address Change for Assignment Recorded at Reel/Frame 039767/0695
Sep 10, 2020
Reel 53731, frame 376
Toprol Acquisition LLCXspire Pharma, LLCAssignment of Assignor's Interest
Oct 12, 2020
Reel 54027, frame 47
Aralez Pharmaceuticals Trading DacToprol Acquisition LLCAssignment of Assignor's Interest

Sources

Google Patents · The patent document at USPTO · Assignment records at USPTO

USPTO account required: This application in Patent Center · USPTO's maintenance fee lookup

Maintenance fee events come from USPTO's own fee records. Its fee lookup asks for the patent number and the application number.

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