Methotrexate Adjuvants to Reduce Toxicity and Methods for Using the Same

US 9,382,287 Surrendered on reissue

Surrendered on reissue Oct 13, 2020 · Low confidence

Computed 20-year base term

Surrendered on reissue Oct 13, 2020 · its term and maintenance fees continue in US RE48,253.

Filed Oct 6, 2014 as application 14/507,622 · Granted Jul 5, 2016

Base term, 20 years from filing, plus 3 days of patent term adjustment (USPTO delay) · capped by a resolved terminal disclaimer

Today

Surrendered Oct 13, 2020

2009 2029

Clock starts
Mar 2, 2009

No longer in force
Oct 13, 2020

Granted
Jul 5, 2016

Term would have run to
Mar 2, 2029

base term after the term ends fee events Updated Nov 14, 2026 · includes USPTO assignment & status data published Nov 14, 2026 and grant & fee data published Nov 10, 2026 (weekly) · how we know

Days of term adjustment

Read from the USPTO patent term adjustment record, not recalculated here.

Capped

Terminal disclaimer

Resolved from the filed document, referencing US 7,998,967, US 8,853,227.

1 of 3

Maintenance fees paid

Fees paid on this patent before its reissue. Those after fall due on the reissue, which carries the term on.

How we calculated this date

One row per rule, each showing its own input and what it did to the date. A step we could not verify says so instead of resolving itself.

Step	Input	Date after this step	Confidence
Base term, 20 years from filing	Clock starts Mar 2, 2009, when the earliest non-provisional application in its chain was filed (this one was filed Oct 6, 2014)	Mar 2, 2029	High confidence
Continuity chain	Every parent in the chain resolved	no change	High confidence
Patent term adjustment	+3 days, USPTO patent term adjustment record	Mar 5, 2029	High confidence
Terminal disclaimer cap	Disclaimer resolved from the filed document (refs US 7,998,967, US 8,853,227)	capped to Mar 2, 2029	High confidence
Patent term extension	None on file	no change	High confidence
Fee events	No fee event states this; the fee state is read from the payments the fee record holds; the fee record shows no payment for this window, and USPTO's status still reads "Patented Case"	no change	Low confidence
Reissue	US RE48,253 issued Oct 13, 2020, and this patent's term continues in it (35 U.S.C. 251, 252)	surrendered Oct 13, 2020	High confidence
Surrendered on reissue	The steps above, in order	Oct 13, 2020	Low confidence

Sources

Google Patents · The patent document at USPTO · Assignment records at USPTO

USPTO account required: This application in Patent Center · USPTO's maintenance fee lookup

Maintenance fee events come from USPTO's own fee records. Its fee lookup asks for the patent number and the application number.

Not on this page: the patent's family, its recorded assignments and its citation count. USPTO's assignment records, linked above, list every recorded assignment.

Every date shows its work: the base term, any term adjustment or extension, any disclaimer cap, and the maintenance fee record, each with a confidence tier. How this record was built

Computed patent terms end on the dates shown. Related patents and pending applications may cover overlapping subject matter.

Methotrexate Adjuvants to Reduce Toxicity and Methods for Using the Same

Surrendered on reissue Oct 13, 2020 · Low confidence

20-year base term ends Mar 2, 2029

How we calculated this date

Sources